[3] Florida State 31-24 Clemson [12] 2023-09-23 16:00
Stadium: Memorial Stadium Round: 1
Home Manager: Dabo Swinney Away Manager: Mike Norvell
Head to Head
| NCAAF | 2022/10/15 23:30 | Clemson v Florida State | L | 34-28 |
| NCAAF | 2021/10/30 19:30 | Florida State v Clemson | L | 20-30 |
| NCAAF | 2019/10/12 19:30 | Clemson v Florida State | L | 45-14 |
| NCAAF | 2018/10/27 16:00 | Florida State v Clemson | L | 10-59 |
| NCAAF | 2018/10/27 16:00 | Clemson v Florida State | L | 59-10 |
| NCAAF | 2017/11/11 20:30 | Florida State v Clemson | L | 14-31 |
| NCAAF | 2016/10/30 00:00 | Clemson v Florida State | L | 37-34 |
| NCAAF | 2015/11/07 20:30 | Clemson v Florida State | L | 23-13 |
| NCAAF | 2014/09/21 00:00 | Florida State v Clemson | W | 23-17 |
| NCAAF | 2012/09/22 12:00 | Florida State v Clemson | W | 49-37 |
| NCAAF | 2011/09/24 12:00 | Clemson v Florida State | L | 35-30 |
| NCAAF | 2010/11/13 12:00 | Florida State v Clemson | W | 16-13 |
| NCAAF | 2009/11/07 12:00 | Clemson v Florida State | L | 40-24 |
| NCAAF | 2008/11/08 12:00 | Florida State v Clemson | W | 41-27 |
| NCAAF | 2007/09/03 12:00 | Clemson v Florida State | L | 24-18 |
| NCAAF | 2006/09/16 12:00 | Florida State v Clemson | L | 20-27 |
| NCAAF | 2005/11/12 12:00 | Clemson v Florida State | L | 35-14 |
| NCAAF | 2004/09/25 12:00 | Florida State v Clemson | W | 41-22 |
| NCAAF | 2003/11/08 12:00 | Clemson v Florida State | L | 26-10 |
| NCAAF | 2002/10/03 12:00 | Florida State v Clemson | W | 48-31 |
| NCAAF | 2001/11/03 12:00 | Clemson v Florida State | W | 27-41 |
| NCAAF | 2000/11/04 12:00 | Florida State v Clemson | W | 54-7 |