Stadium: Albert J. Sloan–Alumni Stadium Round: 1
| NCAAF | 2021/10/30 22:00 | Edward Waters Tigers v Miles Golden Bears | W | 9-16 |
| NCAAF | 2019/10/19 22:00 | Edward Waters Tigers v Miles Golden Bears | W | 28-49 |
| NCAAF | 2022/10/22 19:00 | Miles Golden Bears v Kentucky Thorobreds | L | 7-35 |
| NCAAF | 2022/10/15 21:00 | Miles Golden Bears v Lane College Dragons | L | 32-35 |
| NCAAF | 2022/10/08 18:00 | Benedict College v Miles Golden Bears | L | 20-3 |
| NCAAF | 2022/10/01 18:00 | Albany State Golden Rams v Miles Golden Bears | L | 20-3 |
| NCAAF | 2022/09/24 17:00 | Central State v Miles Golden Bears | W | 14-34 |
| NCAAF | 2022/09/17 23:00 | Miles Golden Bears v Valdosta State | L | 7-55 |
| NCAAF | 2022/09/10 23:00 | Miles Golden Bears v West Alabama Tigers | L | 0-31 |
| NCAAF | 2022/09/03 22:00 | Alabama State v Miles Golden Bears | L | 21-13 |
| NCAAF | 2022/10/22 17:00 | Central State v Edward Waters Tigers | W | 13-45 |
| NCAAF | 2022/10/15 17:00 | North Carolina A&T v Edward Waters Tigers | L | 45-7 |
| NCAAF | 2022/10/08 22:00 | Edward Waters Tigers v Albany State Golden Rams | L | 7-55 |
| NCAAF | 2022/10/02 18:00 | Edward Waters Tigers v Morehouse College Maroon Tigers | W | 49-20 |
| NCAAF | 2022/09/24 19:00 | Lane College Dragons v Edward Waters Tigers | L | 20-9 |
| NCAAF | 2022/09/10 22:00 | Edward Waters Tigers v Savannah State | L | 28-31 |
| NCAAF | 2022/09/03 20:00 | Edward Waters Tigers v Clark Atlanta University | L | 34-39 |
| NCAAF | 2022/08/27 20:00 | Florida Memorial University Lions v Edward Waters Tigers | L | 39-34 |