Home History
| Anglia - Premier League 2 | 2022/08/26 18:00 | Newcastle U21 v Derby U21 | L | 4-0 |
| Anglia - Premier League 2 | 2022/08/21 12:00 | Derby U21 v Sunderland U21 | L | 0-4 |
| Anglia - Premier League 2 | 2022/08/12 17:00 | Middlesbrough U21 v Derby U21 | L | 3-1 |
| Anglia - Premier League 2 | 2022/08/05 17:00 | Derby U21 v Leeds U21 | L | 2-5 |
| Anglia - Premier League 2 | 2016/08/26 12:00 | Derby U21 v Tottenham U21 | L | 1-2 |
| Anglia - Premier League 2 | 2016/08/22 18:00 | Everton U21 v Derby U21 | L | 2-0 |
| Anglia - Premier League 2 | 2016/08/15 18:00 | Derby U21 v Man City U21 | L | 2-3 |
Away History
| Anglia - EFL Trophy | 2022/08/30 18:00 | Forest Green v Southampton U21 | L | 3-1 |
| Anglia - Premier League 2 | 2022/08/26 18:00 | Southampton U21 v Norwich U21 | D | 1-1 |
| Anglia - Premier League 2 | 2022/08/19 18:00 | Stoke U21 v Southampton U21 | W | 0-3 |
| Anglia - Premier League 2 | 2022/08/12 17:00 | Southampton U21 v West Brom U21 | W | 4-1 |
| Anglia - Premier League 2 | 2022/08/08 18:00 | Nottm Forest U21 v Southampton U21 | W | 1-3 |
| Anglia - EFL Trophy | 2021/11/09 19:00 | Crawley Town v Southampton U21 | W | 0-4 |
| Anglia - EFL Trophy | 2021/10/05 18:00 | Charlton v Southampton U21 | L | 4-1 |
| Anglia - EFL Trophy | 2021/09/14 18:00 | Leyton Orient v Southampton U21 | L | 1-0 |