Stadium: Quadra Central Round: 25 Ground: Clay
| Challenger Florianopolis | 2021/12/08 17:50 | Facundo Juarez v Facundo Diaz Acosta | 3-6,7-5,6-2 |
| Challenger Florianopolis | 2021/12/06 16:35 | Facundo Diaz Acosta v Kaichi Uchida | 6-4,6-3 |
| Challenger Sao Paulo | 2021/12/03 13:00 | Facundo Diaz Acosta v Luciano Darderi | 3-6,4-6 |
| Challenger Sao Paulo | 2021/12/02 17:00 | Thiago Seyboth Wild v Facundo Diaz Acosta | 3-6,5-7 |
| Challenger Sao Paulo | 2021/11/30 16:55 | Facundo Diaz Acosta v Gonzalo Villanueva | 7-5,6-1 |
| Challenger Brasilia | 2021/11/23 20:50 | Thiago Seyboth Wild v Facundo Diaz Acosta | 7-6,6-3 |
| Challenger Campinas | 2021/11/14 16:00 | Facundo Diaz Acosta v Joao Lucas Reis da Silva | 4-6,6-7 |
| Challenger Guayaquil | 2021/11/02 15:00 | Facundo Juarez v Facundo Diaz Acosta | 3-6,6-4,6-4 |
| Challenger Florianopolis | 2021/12/06 15:40 | Pablo Cuevas v Nicolas Alvarez Varona | 7-6,6-2 |
| Challenger Sao Paulo | 2021/12/02 15:30 | Luciano Darderi v Nicolas Alvarez Varona | 6-4,6-1 |
| Challenger Sao Paulo | 2021/11/29 16:55 | Nicolas Alvarez Varona v Nicolas Kicker | 7-5,6-3 |
| Challenger Brasilia | 2021/11/23 15:50 | Bogdan Bobrov v Nicolas Alvarez Varona | 3-6,6-7 |
| Challenger Campinas | 2021/11/18 14:00 | Nicolas Alvarez Varona v Santiago Rodriguez Taverna | 6-7,7-6,5-7 |
| Challenger Campinas | 2021/11/16 15:50 | Orlando Luz v Nicolas Alvarez Varona | 3-6,4-6 |
| Challenger Campinas | 2021/11/15 13:30 | Bogdan Bobrov v Nicolas Alvarez Varona | 5-7,2-6 |
| Challenger Campinas | 2021/11/14 16:00 | Nicolas Alvarez Varona v Genaro Alberto Olivieri | 6-3,3-6,7-6 |