[10] Wasps 26-20 Northampton [3] 2021-10-10 14:00
Stadium: Ricoh Arena Round: 4
Referee: Craig Maxwell-Keys
Head to Head
| Premiership Rugby | 2021/05/29 15:30 | Northampton v Wasps | L | 30-25 |
| Premiership Rugby | 2021/02/06 13:00 | Wasps v Northampton | L | 17-22 |
| Premiership Rugby | 2020/08/16 14:00 | Northampton v Wasps | W | 21-34 |
| Premiership Rugby | 2020/01/05 15:00 | Wasps v Northampton | L | 31-35 |
| Premiership Rugby Cup | 2019/09/28 14:00 | Northampton v Wasps | W | 32-36 |
| Premiership Rugby | 2019/01/06 15:00 | Wasps v Northampton | W | 27-16 |
| Premiership Rugby | 2018/11/17 13:00 | Northampton v Wasps | L | 36-17 |
| Premiership Rugby Cup | 2018/11/04 15:00 | Wasps v Northampton | L | 14-15 |
Home History
| Premiership Rugby | 2021/10/02 14:00 | Newcastle Falcons v Wasps | L | 18-14 |
| Premiership Rugby | 2021/09/25 14:00 | Wasps v Bristol | W | 44-8 |
| Premiership Rugby | 2021/06/12 14:00 | Wasps v Leicester | L | 31-38 |
| Premiership Rugby | 2021/06/05 15:30 | London Irish v Wasps | W | 36-39 |
| Premiership Rugby | 2021/05/29 15:30 | Northampton v Wasps | L | 30-25 |
| Premiership Rugby | 2021/05/15 14:00 | Wasps v Worcester Warriors | W | 23-19 |
| Premiership Rugby | 2021/05/09 14:00 | Harlequins v Wasps | L | 48-46 |
| Premiership Rugby | 2021/04/25 14:00 | Wasps v Bath | W | 39-29 |
Away History
| Premiership Rugby | 2021/10/02 13:00 | Northampton v London Irish | W | 23-21 |
| Premiership Rugby | 2021/09/25 14:00 | Exeter Chiefs v Northampton | W | 24-26 |
| Premiership Rugby | 2021/09/18 14:00 | Northampton v Gloucester | W | 34-20 |
| Premiership Rugby | 2021/06/12 14:00 | Bath v Northampton | L | 30-24 |
| Premiership Rugby | 2021/06/06 14:00 | Northampton v Exeter Chiefs | L | 26-29 |
| Premiership Rugby | 2021/05/29 15:30 | Northampton v Wasps | W | 30-25 |
| Premiership Rugby | 2021/05/17 18:30 | Newcastle Falcons v Northampton | L | 18-10 |
| Premiership Rugby | 2021/05/08 13:00 | Northampton v Gloucester | L | 7-31 |