Stadium: Jayne Stadium Round: 1
Home Manager: Rob Tenyer Away Manager: Brian Young
| NCAAF | 2021/03/20 16:00 | Stetson Hatters v Morehead State | L | 14-31 |
| NCAAF | 2019/11/23 18:00 | Stetson Hatters v Morehead State | W | 31-16 |
| NCAAF FCS | 2018/11/03 17:00 | Morehead State v Stetson Hatters | W | 24-48 |
| NCAAF | 2017/10/21 17:00 | Morehead State v Stetson Hatters | L | 29-26 |
| NCAAF | 2021/11/06 17:00 | Dayton v Stetson Hatters | L | 41-13 |
| NCAAF | 2021/10/30 17:00 | Stetson Hatters v Presbyterian | W | 56-14 |
| NCAAF | 2021/10/16 17:00 | St.Thomas MIN v Stetson Hatters | L | 38-7 |
| NCAAF | 2021/10/09 16:00 | Stetson Hatters v Marist | L | 3-34 |
| NCAAF | 2021/10/02 17:00 | Davidson Wildcats v Stetson Hatters | L | 35-28 |
| NCAAF | 2021/09/25 17:00 | Stetson Hatters v Princeton | L | 0-63 |
| NCAAF | 2021/09/11 22:00 | Stetson Hatters v Ave Maria Gyrenes | W | 49-16 |
| NCAAF | 2021/09/04 22:00 | Stetson Hatters v Warner Royals | W | 54-14 |
| NCAAF | 2021/11/06 20:00 | Morehead State v San Diego | L | 3-10 |
| NCAAF | 2021/10/30 18:00 | Davidson Wildcats v Morehead State | L | 29-22 |
| NCAAF | 2021/10/23 16:00 | Morehead State v Marist | W | 27-24 |
| NCAAF | 2021/10/16 19:00 | Butler v Morehead State | W | 8-31 |
| NCAAF | 2021/10/09 17:00 | Morehead State v Presbyterian | W | 38-30 |
| NCAAF | 2021/10/02 18:00 | Dayton v Morehead State | W | 38-45 |
| NCAAF | 2021/09/18 19:00 | Morehead State v Austin Peay | L | 35-59 |
| NCAAF | 2021/09/04 22:00 | Morehead State v James Madison | L | 10-68 |