[12] Southampton 1-2 Wolverhampton [14] 2021-02-14 12:00
Stadium: St. Mary's Stadium Round: 24
Referee: Graham Scott Home Manager: Ralph Hasenhuttl Away Manager: Nuno Espirito Santo
Head to Head
| Anglia - FA Cup | 2021/02/11 17:30 | Wolverhampton v Southampton | W | 0-2 |
| Anglia - Premier League | 2020/11/23 20:00 | Wolverhampton v Southampton | D | 1-1 |
| Anglia - Premier League | 2020/01/18 15:00 | Southampton v Wolverhampton | L | 2-3 |
| Anglia - Premier League | 2019/10/19 14:00 | Wolverhampton v Southampton | D | 1-1 |
| Anglia - Premier League | 2019/04/13 14:00 | Southampton v Wolverhampton | W | 3-1 |
| Anglia - Premier League | 2018/09/29 14:00 | Wolverhampton v Southampton | L | 2-0 |
| Anglia - EFL Cup | 2017/08/23 18:45 | Southampton v Wolverhampton | L | 0-2 |
Home History
| Anglia - FA Cup | 2021/02/11 17:30 | Wolverhampton v Southampton | W | 0-2 |
| Anglia - Premier League | 2021/02/06 15:00 | Newcastle v Southampton | L | 3-2 |
| Anglia - Premier League | 2021/02/02 20:15 | Man Utd v Southampton | L | 9-0 |
| Anglia - Premier League | 2021/01/30 20:00 | Southampton v Aston Villa | L | 0-1 |
| Anglia - Premier League | 2021/01/26 20:15 | Southampton v Arsenal | L | 1-3 |
| Anglia - FA Cup | 2021/01/23 12:15 | Southampton v Arsenal | W | 1-0 |
| Anglia - FA Cup | 2021/01/19 20:00 | Southampton v Shrewsbury | W | 2-0 |
| Anglia - Premier League | 2021/01/16 20:00 | Leicester v Southampton | L | 2-0 |
Away History
| Anglia - FA Cup | 2021/02/11 17:30 | Wolverhampton v Southampton | L | 0-2 |
| Anglia - Premier League | 2021/02/07 14:00 | Wolverhampton v Leicester | D | 0-0 |
| Anglia - Premier League | 2021/02/02 18:00 | Wolverhampton v Arsenal | W | 2-1 |
| Anglia - Premier League | 2021/01/30 15:00 | Crystal Palace v Wolverhampton | L | 1-0 |
| Anglia - Premier League | 2021/01/27 18:00 | Chelsea v Wolverhampton | D | 0-0 |
| Anglia - FA Cup | 2021/01/22 19:45 | Chorley v Wolverhampton | W | 0-1 |
| Anglia - Premier League | 2021/01/16 12:30 | Wolverhampton v West Brom | L | 2-3 |
| Anglia - Premier League | 2021/01/12 20:15 | Wolverhampton v Everton | L | 1-2 |