[8] Rostov 2-3 Spartak Moskwa [2] 2021-04-04 16:00
Stadium: Rostov Arena Round: 24
Referee: Pavel Kukuyan Home Manager: Valeri Karpin Away Manager: Domenico Tedesco
Head to Head
| Rosja - Premier League | 2020/10/31 13:30 | Spartak Moskwa v Rostov | W | 0-1 |
| Europa - Towarzyskie | 2020/02/01 15:00 | Spartak Moskwa v Rostov | L | 2-1 |
| Rosja - Premier League | 2019/12/08 16:00 | Spartak Moskwa v Rostov | W | 1-4 |
| Puchar Rosji | 2019/10/31 16:30 | Spartak Moskwa v Rostov | L | 2-1 |
| Rosja - Premier League | 2019/07/20 18:30 | Rostov v Spartak Moskwa | D | 2-2 |
| Europa - Towarzyskie | 2019/06/26 16:00 | Rostov v Spartak Moskwa | W | 2-0 |
| Rosja - Premier League | 2019/04/14 16:00 | Rostov v Spartak Moskwa | W | 2-1 |
| Europa - Towarzyskie | 2019/01/21 17:00 | Spartak Moskwa v Rostov | L | 2-1 |
Home History
| Rosja - Premier League | 2021/03/17 15:00 | Rotor Volgograd v Rostov | W | 0-4 |
| Rosja - Premier League | 2021/03/12 16:00 | FK Khimki v Rostov | L | 1-0 |
| Rosja - Premier League | 2021/03/06 16:00 | Rostov v PFC Sochi | D | 0-0 |
| Rosja - Premier League | 2021/02/27 13:30 | Zenit St Petersburg v Rostov | D | 2-2 |
| Puchar Rosji | 2021/02/21 16:30 | Rostov v FC Akhmat Grozny | L | 0-1 |
| Europa - Towarzyskie | 2021/02/14 14:34 | Lokomotiv Moskwa v Rostov | L | 2-1 |
| Europa - Towarzyskie | 2021/02/11 11:30 | Atletico Sanluqueno v Rostov | D | 0-0 |
| Europa - Towarzyskie | 2021/02/08 15:30 | Lokomotiv Tbilisi v Rostov | W | 1-4 |
Away History
| Rosja - Premier League | 2021/03/18 16:00 | Spartak Moskwa v Ural | W | 5-1 |
| Rosja - Premier League | 2021/03/13 16:00 | Dinamo Moskwa v Spartak Moskwa | W | 1-2 |
| Rosja - Premier League | 2021/03/07 16:00 | Spartak Moskwa v Krasnodar | W | 6-1 |
| Rosja - Premier League | 2021/02/28 11:00 | Spartak Moskwa v Rubin Kazan | L | 0-2 |
| Puchar Rosji | 2021/02/20 16:30 | Dinamo Moskwa v Spartak Moskwa | L | 2-0 |
| Europa - Towarzyskie | 2021/02/07 12:00 | Spartak Moskwa v Riga FC | W | 4-0 |
| Europa - Towarzyskie | 2021/02/06 12:00 | Spartak Moskwa v Shakhter Soligorsk | W | 2-1 |
| Europa - Towarzyskie | 2021/01/30 12:00 | Spartak Moskwa v Pakhtakor Tashkent | W | 2-1 |